Did a E85 dyno tune the other day and if that fuel is available it's a nice way to go. Used a Quick Fuel 850 which is "kind of" like a 850 DP Holley. Not a bad carb but not as nice of castings as you tyically see from Holley. A few things on dialing in after first start. Float levels for E85 need to be well above 1/2 up the sight glass, at least in a 600 horse applilcation. We needed to set the float level at the top of the sight glass to keep floats near the 1/2 point during a pull. With E85 float level has a PROFOUND affect on the fuel curve. Setting up the 4 corner idle was somewhat time consuming. Lots of playing around on the secondaries to get all 4 to respond equal. This carb never did quite fuel at idle, or through the power band, as well as a stock style Holley 750 HP. Small idle adjustments seemed to make big changes so think tic turn here not quarter turns. Once in the car will want to fine tune the idle in for sure. Overall power curve was exactly the same. Maybe lost a tad of torque low and mid but HP was basically the same up top and after peak. There is no doubt, lots of fuel flow is required with E85. NO doubt though with high compression, 12:1 and if it's available, it is a very effective way to lower fuel costs versus race gas.